UPSC PYQPrelims 2021

Civil Services Examination · Question 66

In the context of hereditary diseases, consider the following statements: 1. Passing on mitochondrial diseases from parent to child can be prevented by mitochondrial replacement therapy either before or after in vitro fertilization of egg. 2. A child inherits mitochondrial diseases entirely from mother and not from father. Which of the statements given above is/are correct?

  1. 1 only
  2. 2 only
  3. Both 1 and 2
  4. Neither 1 nor 2
Show answer & explanation

Answer: (C) Both 1 and 2

Explanation

MRT (spindle transfer before, or pronuclear transfer after fertilisation) can prevent transmission, and mitochondrial DNA is inherited maternally.